Specifically identified Ayurvedic preparations is recommended by ministry of AYUSH as post-exposure prophylaxis to efficaciously prevent a negative person who has come into contact with COVID-19-positive. Traditionally, recommended Ayurvedic preparations have been used as antioxidants, antimicrobial and anti-inflammatory properties. Particularly, Guduchi Ghanvati has been recognised with its ability to control viral attachment, viral replication and induce immune response in pre clinical settings, and found to be one among the most important drugs in Ayurveda to fight against COVID-19. However, known gap in guideline implementation and its impact on preventing active infection in exposed cases is unclear. Study aimed to increase the use of recommended AYUSH guidelines by having registered AYUSH physicians provide these medications, when indicated, in community based participants after known exposure to the SARS-CoV-2 coronavirus.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
216
500 mg of Samshamani vati or Giloy Ghanavati (Aqueous extract of Tinospora cordifolia) twice daily
Practice guidelines to follow physical distancing, respiratory and hand hygiene, wear mask
NMP Medical Research Institute
Jaipur, Rajasthan, India
Padmnabham Ayurveda Hospital & Research Center
Jaipur, Rajasthan, India
Number of participants with active COVID-19
PCR- proven COVID-19
Time frame: 14-days following exposure
Time to symptoms onset
Days until start of symptoms of COVID-19
Time frame: 14-days
Disease Severity
Visual Analog Scale of rating overall symptom severity (0 = no symptoms; 10 = most severe)
Time frame: 14 days
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