Diabetes Mellitus individuals are known to have dietary rules, namely regulating the amount, type and time of eating. Ramadan fasting seems to be beneficial for people who want to reduce their weight, but it is not easy for diabetic patients. Because of its distinctive features, Ramadhan induces changes in eating habits, calorie consumption, sleeping patterns, and daily physical activity, which may contribute to changes in hunger-satiety responses and glicemic control. Examining changes in gut hormones during Ramadan fasting may reveal whether this observance could change glucose metabolism in diabetics without triggering the undesirable effect of gluconeogenesis. The proportions of fat, protein, and carbohydrate in meals vary between outside and within Ramadan. Alterations in timing and composition meal during Ramadan lead to reduced food intake may affect gut hormones and metabolic responses. The aim of this study to determine whether the effect of Ramadan fasting differed in people with DM patients, pre-DM and healthy individuals, with respect to gut hormones, body composition, metabolic parameters, and glycemic control
The experimental study was performed during and after Ramadan fasting in 2021 (April to May) in Semarang, Indonesia. The present study was performed using the quasy-experimental method by pre-post measurement of three experimental groups (diabetics, Obese and healthy subjects) selected using the purposive sampling methods
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
45
subject conduct fasting in Ramadan for 30 days
Etika Ratna Noer
Semarang, Central Java, Indonesia
change acylated ghrelin
Change from Baseline acyl ghrelin at 30 days taken in the lab from venous blood specimen
Time frame: 30 days
change PYY
Change from Baseline PYY at 30 days taken in the lab from venous blood specimen
Time frame: 30 days
change GLP-1
Change from Baseline GLP-1 at 30 days taken in the lab from venous blood specimen
Time frame: 30 days
change insulin
Change from Baseline Insulin at 30 days taken in the lab from venous blood specimen
Time frame: 30 days
change body weight
Change from Baseline body weight at 30 days
Time frame: 30 days
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