Donor sperm provides a viable option for patients with significant male factor infertility. However, since the source of sperm is not from the male partner, the psychological burden of these couples is more pronounced and complex than other patients.The purpose of this study is to investigate the stress faced by participants undergoing assisted reproduction with donor sperm and to further investigate its impact on pregnancy outcomes.
The number of infertility patients has increased significantly in recent years, and infertility caused by the male partner accounts for about 30%-50% of infertility factors. Donor sperm provides a viable option for patients with significant male factor infertility. However, since the source of sperm is not from the male partner, the psychological burden of these couples is more pronounced and complex than other patients. Many factors such as social, marital, and family problems may contribute to their depressed emotional state. And the impact of these negative emotions on pregnancy outcomes cannot be ignored. In this study, investigators intend to investigate the stress faced by participants undergoing assisted reproduction with donor sperm to provide a reliable basis for future psychological interventions and health education for this group of patients and improve the quality of life of infertility patients.
Study Type
OBSERVATIONAL
Enrollment
200
One group use donor sperm through the process of assisted reproduction and the other uses husband's semen.
Women's Hospital, School of Medicine, Zhejiang University
Hangzhou, Zhejiang, China
RECRUITINGImplantation rate
Implantation rate is defined as number of sacs per embryo transferred.
Time frame: 8 months
clinical pregnancy rate
presence of at least one gestational sac on ultrasound of 6 weeks
Time frame: 8 months
fertilization rate
No. of fertilized oocyte divided by No. of inseminated cumulus-oocyte complexes (COCs)
Time frame: 8 months
cleavage rate
No. of cleaved embryo divided by No. of fertilized oocyte
Time frame: 8 months
Total gonadotropin use
Total gonadotropin use of each participant
Time frame: 8 months
Ovarian hyperstimulation syndrome (OHSS) rates
OHSS rates in both study groups
Time frame: 8 months
Number of oocytes retrieved
Time frame: 8 months
Metaphase II (MII) oocytes
the number of mature oocytes
Time frame: 8 months
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