The purpose of the research is to evaluate kinetic after vaccination to the COVID-19 coronavirus by measurements of specific and neutralizant antibodies for spike antigenic sequences . This work will allow us to follow the efficacy and tolerance of the vaccine over a year, to evaluate the antibody profile, their kinetics, the fraction of neutralising antibodies and will also allow us to understand the attitudes to be taken to ensure the best protection for our staff
Our objective is to follow the hospital staff after vaccination, for this we will include two groups of participants: G1: vaccinated staff who did not contract the virus (at the date of vaccination) and who had a serology \<0 at least at D7 of the date of vaccination dose 1 (known serological value) G2: vaccinated personnel who have contracted the virus with a PCR + and who have positive serology at least at D7 of the date of vaccination (known serological value)
Study Type
OBSERVATIONAL
Enrollment
300
Blood sampling (4 per year)
HMPIT vaccination committee
Tunis, Please Select..., Tunisia
RECRUITINGVaccine effectiveness
Vaccine effectiveness as measured by the number of positive PCRs in one year
Time frame: 1 year
Vaccine effectiveness
antibody kinetics
Time frame: 1 year
the tolerance of the vaccine
post-vaccination adverse event
Time frame: 1 year
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