Current Use in Intensive Care Units by Intensivists of Antihypertensive Drugs

Assistance Publique - Hôpitaux de Paris200 enrolled

Overview

Multicenter, prospective and observational study of practices and impacts of the use of antihypertensive therapies in intensive medicine and intensive care

Multicenter, prospective observational cohort study on 200 patients, by doctor's questionnaire on the prescription of antihypertensive drugs in intensive care, follow-up over 72 hours of the prescription.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Antihypertensive Drugs in ICU

Interventions

Inventory of prescribing habits and detect any differences in efficacy and tolerance of antihypertensive drugsOTHER

* Time to monitor blood pressure values in target targets * Need for administration of another antihypertensive drug * Disappearance of organ failure attributable to hypertension * Weaning from an extra-renal purification * Weaning from mechanical ventilation * Improved kidney function * Iatrogenic hypotension * Need for suspension of treatment * Other side effect

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patient * Admitted to an intensive care unit * Patient having presented a state of circulatory shock, defined by the need for continuous administration of a vasopressive amine for at least one hour, among: Noradrenaline, Adrenaline * In whom the introduction of drug treatment for antihypertensive purposes is decided Exclusion Criteria: * Patient admitted to intensive care for a hypertensive emergency (hypertensive surge or malignant arterial hypertension leading to organ dysfunction * Patient who has already received at least one anti-hypertensive drug during his stay in intensive care * Cerebro-injured patient, proven or suspected cerebral edema, head trauma \<1 month, decrease in cerebral perfusion measured * Proven or suspected active bleeding * Patient refusal of participation

Locations (7)

Intensive Care Victor Dupouy Hospital

Argenteuil, France

RECRUITING

Intensive Care Avicenne Hsopital

Bobigny, France

RECRUITING

Intensive Care Louis Mourier Hospital

Colombes, France