The purpose of this study is to access the clinical characteristics and risk factors for neurological sequelae after acute carbon monoxide poisoning.
After being informed about the study and potential risks, patients meet the inclusion criteria would be given informed consent and entry the study. The data will be collected according to self-designed questionnaire, including :1) The baseline characteristics: would be recorded 6 hours after patients presentation;2) Patients' self evaluation for discomfort symptoms: would be recorded at day 0, week 1, 3 and 6, month 6 and 12；3) Neurological function: would be recorded at day 0, week 6, month 6 and 12.
Study Type
OBSERVATIONAL
Enrollment
1,250
No intervention will be given
First Hospital of Jilin University
Changchun, Jilin, China
Changes of Mini-mental State Examination (MMSE) score at 6 weeks
Score ranges from 0 to 30, a lower score means a worse outcome.
Time frame: Changes of score from baseline to 6 weeks
Changes of Mini-mental State Examination (MMSE) score at 6 months
Score ranges from 0 to 30, a lower score means a worse outcome.
Time frame: Changes of score from baseline to 6 months
Changes of Mini-mental State Examination (MMSE) score at 12 months
Score ranges from 0 to 30, a lower score means a worse outcome.
Time frame: Changes of score from baseline to 12 months
Changes of Montreal cognitive assessment (MoCA）score at 6 weeks
Score ranges from 0 to 30, a lower score means a worse outcome.
Time frame: Changes of score from baseline to 6 weeks
Changes of Montreal cognitive assessment (MoCA）score at 6 months
Score ranges from 0 to 30, a lower score means a worse outcome.
Time frame: Changes of score from baseline to 6 months
Changes of Montreal cognitive assessment (MoCA）score at 12 months
Score ranges from 0 to 30, a lower score means a worse outcome.
Time frame: Changes of score from baseline to 12 months
Changes of Hamilton Depression Scale(HAMD) score at 6 weeks
Score ranges from 0 to 54, a higher score means a worse outcome.
Time frame: Changes of score from baseline to 6 weeks
Changes of Hamilton Depression Scale(HAMD) score at 6 months
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Score ranges from 0 to 54, a higher score means a worse outcome.
Time frame: Changes of score from baseline to 6 months
Changes of Hamilton Depression Scale(HAMD) score at 12 months
Score ranges from 0 to 54, a higher score means a worse outcome.
Time frame: Changes of score from baseline to 12 months
Changes of Hamilton Anxiety Scale (HAMA) score at 6 weeks
Score ranges from 0 to 56, a higher score means a worse outcome.
Time frame: Changes of score from baseline to 6 weeks
Changes of Hamilton Anxiety Scale (HAMA) score at 6 months
Score ranges from 0 to 56, a higher score means a worse outcome.
Time frame: Changes of score from baseline to 6 months
Changes of Hamilton Anxiety Scale (HAMA) score at 12 months
Score ranges from 0 to 56, a higher score means a worse outcome.
Time frame: Changes of score from baseline to 12 months
Changes of Activity of Daily Living (ADL) score at 6 weeks
Score ranges from 0 to 80, a higher score means a worse outcome.
Time frame: Changes of score from baseline to 6 weeks
Changes of Activity of Daily Living (ADL) score at 6 months
Score ranges from 0 to 80, a higher score means a worse outcome.
Time frame: Changes of score from baseline to 6 months
Changes of Activity of Daily Living (ADL) score at 12 months
Score ranges from 0 to 80, a higher score means a worse outcome.
Time frame: Changes of score from baseline to 12 months
Changes of self-evaluation of discomfort symptoms scale at 1 week
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome
Time frame: Changes of score from baseline to 1 week
Changes of self-evaluation of discomfort symptoms scale at 3 weeks
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome
Time frame: Changes of score from baseline to 3 weeks
Changes of self-evaluation of discomfort symptoms scale at 6 weeks
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome
Time frame: Changes of score from baseline to 6 weeks
Changes of self-evaluation of discomfort symptoms scale at 6 months
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome
Time frame: Changes of score from baseline to 6 months
Changes of self-evaluation of discomfort symptoms scale at 12 months
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome
Time frame: Changes of score from baseline to 12 months
Rates of cardiovascular and cerebrovascular events
Cardiovascular and cerebrovascular events includes：cardiac arrest, myocardial infarction, cerebral hemorrhage, and cerebral infarction. A patient develops any of the former diseases during following up would be record as 1 event.
Time frame: through study completion, an average of 1 year
Rates of accidental injury
Accidental injuries may include accidental fall, fracture, traffic accident etc. A patient develops any of the former during following up would be record as 1 event.
Time frame: through study completion, an average of 1 year