Exploratory Study on Safety of PEEK Knee Prosthesis

Inclusion Criteria: * Male and female subjects aged 55 years of age or older and less than 74 years of age, younger subjects should have urgent need for surgery. * Subjects skeletal maturity. * Subjects appropriate for total knee replacement, such as noninflammatory degenerative joint diseases (such as osteoarthritis, traumatic arthritis, or ischemic necrosis); Inflammatory degenerative joint diseases (including rheumatoid arthritis); Correction of functional deformity. * The diseased side knee appropriate for primary total knee arthroplasty . * Subjects or guardian is willing and able to sign the informed consent form . Exclusion Criteria: * Subjects with knee instability or abnormal gait caused by neuromuscular insufficiency. * Subjects with bilateral knee joint disease who are expected to require replacement of both knees during the course of the study (i.e., within the next 12 months) . * Alcoholics, drug addicts and drug abusers. * Subjects with severe diabetes (fasting blood glucose \> 10mmol/L) * Body Mass Index, BMI\>35. * Female subjects who are pregnant or lactating. * Subjects have disease limited their participation in the investigation or have an existing condition that would compromise their participation and follow-up in this clinical investigation. * In the month before inclusion, subjects who participated in clinical studies of other drugs, biological agents or medical devices and failed to meet the main research endpoints. * Other conditions, in the opinion of the Investigator, are inappropriate for participation in this clinical investigation.