Risk Factors for Long-term Opioid Use

Stanford University1,500,392 enrolled

Overview

Surgeons often see patients with pain to exclude organic pathology and consider surgical treatment. We examined factors associated with long-term opioid therapy among patients with foot/ankle, anorectal, and temporomandibular joint pain to aid clinical decision making. Using the IBM MarketScan® Research Database, we conducted a retrospective cohort analysis of patients aged 18-64 with a clinical encounter for foot/ankle, anorectal, or temporomandibular joint pain (January 2007-September 2015). Multivariable logistic regression was used to estimate adjusted odds ratios for factors associated with long-term opioid therapy, including age, sex, geographic region, pain condition, psychiatric diagnoses, and surgical procedures in the previous year.

Study Type

OBSERVATIONAL

Enrollment

1,500,392

Conditions

Pain Syndrome

Interventions

No intervention - retrospective observational cohort studyOTHER

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * 18-64 years old * at least one encounter for anorectal, foot/ankle, or TMJ pain * Marketscan continuous enrollment for 1 year prior and 1 year after the index pain encounter

Outcomes

Primary Outcomes

Long-term opioid use

opioid prescriptions for 3 months.

Time frame: >90 days of opioid supply

Secondary Outcomes

new long-term opioid use

Opioid prescriptions for over 3 months in patients who have not had prior opioid prescriptions.

Time frame: >90 days of opioid supply

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.