To explore the effects and safety of human albumin in burn shock recovery, and then provide a theoretical basis for its rational use.
A retrospective case-control study was conducted. Patients who admitted to the burn ward and needed fluid resuscitation during the period of January 2011 to December 2018 in our unit were identified. Patients were divided into two groups according to the severity of burns, the patients with a 20%\<TBSA≤50% constituted the moderate and severe burn group, the patients with a TBSA\>50% constituted the severest burn group, and then the patients who used albumin for resuscitation constituted the albumin group, the patients who did not use albumin constituted the control group. The primary outcome was mortality, and the secondary outcomes included hospital stay, ventilator supporting, fluid use, and complications.
Study Type
OBSERVATIONAL
Enrollment
364
At least one dose of human albumin was used for the patients during hospitalization in the burn ward consisted the albumin group. The patients who have no albumin use during their hospitalization in the burn ward consisted the control group.
the mortality of the patients
The mortality of the patients during their hospitalization.
Time frame: during the patients's hospitalization, an average of 1-2 month.
the length of the patients's hospital stay
the Length of the patients's hospital stay,an average of 1-2 month.
Time frame: during the patients's hospitalization, an average of 1-2 month.
the number of patients that using ventilators
the number of patients who using ventilators during their hospitalization
Time frame: during the patients's hospitalization, an average of 1-2 month.
Volume of fluid used for resuscitationVolume of fluid used for resuscitation the volume of the patients's resuscitation fluid
the volume of the patients's resuscitation fluid using "mL" as the measurement
Time frame: during the patients's hospitalization, an average of 1-2 month.
the number of complications that the patients occurred
the number of complications that the patients occurred during their hospitalization
Time frame: during the patients's hospitalization, an average of 1-2 month.
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