PCR Based CEUS in BI RADS 4A Nodules

Second Affiliated Hospital, School of Medicine, Zhejiang University260 enrolled

Overview

The aim of this study was to investigate the added value of Principal Component Regression (PCR) based contrast-enhanced ultrasound (CEUS) for differentiating low risk patients with breast nodules categorized as 4A using the Breast Imaging Reporting and Data System (BI-RADS). The study included patients with 4A nodules confirmed by core biopsy and/or surgery. The CEUS parameters were assessed and PCR scores were calculated to evaluated the added value in BI-RADS 4A nodules.

Study Type

OBSERVATIONAL

Enrollment

260

Conditions

PCA Breast Cancer

Interventions

imagingDIAGNOSTIC_TEST

ultrasound and contrast enhanced ultrasound for BI RADS4A breast modules

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: patients with BI-RADS 4A breast lesion Exclusion Criteria: (i) absence of a pathologic diagnosis; (ii) presence of breast nodules that were too large to compare with normal parenchyma; (iii) patients with radiotherapy and chemotherapy of breast cancer; and (iv) skin disorders.

Locations (1)

SAHZJU

Hanzhou, Zhejiang, China

Outcomes

Primary Outcomes

surgery or biopsy

According to the PCR result, if it's positive, the nodule category was maintained, however, if it's negative, the nodule was downgraded. all nodules were submitted to biopsy or biopsy.

Time frame: up to 3 months

Data from ClinicalTrials.gov

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