Speech Processing in Stuttering

University of Michigan145 enrolled

Overview

This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech. Eligible participants enrolled will complete a variety of computer and speech-based tasks on up to 2 visits.

The study team will update the record to include the secondary identification number once the NIH has released the funds.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

145

Conditions

Stuttering Stuttering, Childhood Stuttering, Adult

Interventions

Speech and non-speech tasksBEHAVIORAL

Participants will complete speech tasks such as listening to and/or producing speech and non-speech sounds.

Eligibility

Sex: ALLMin age: 6 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria (adults who do not stutter): * 18-65 years old * English as primary language * Normal speech, language, hearing, cognition Exclusion criteria: (adults who do not stutter) * Personal or family history of stuttering * Major medical or psychiatric illness Inclusion criteria: (adults who stutter) * Aged 18-65 years * English as primary language * Normal speech, language, hearing, cognition (other than stuttering) * Currently stutters Exclusion criteria: (adults who stutter) * Speech therapy within the past year * Major medical or psychiatric illness Inclusion criteria: (children who do not stutter) * Aged 6 to 17 years * English as primary language * Normal speech, language, hearing, cognition Exclusion criteria: (children who do not stutter) * Personal or family history of stuttering * Major medical or psychiatric illness * Language/motor delay Inclusion criteria: (children who stutter) * Aged 6 to 17 years * English as primary language * Normal speech, language, hearing, cognition (other than stuttering) * Currently stutters Exclusion criteria: (children who stutter) * Major medical or psychiatric illness * Language/motor delay

Locations (2)

University of Michigan

Ann Arbor, Michigan, United States

Michigan State University

East Lansing, Michigan, United States

Outcomes

Primary Outcomes

Phase Locking Value (PLV) - Session 1 Speech Tasks

Participants will hear a series of single syllables spoken rhythmically and will be instructed to whisper the syllable "tah" repeatedly while the recording is playing. The degree of synchronization (how well the participant's whispered syllables match the cadence of the recorded syllables they are listening to) will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals, where 0 is a complete mis-match and a 1 is a perfect match. Adults were not instructed to attempt to match the cadence (Implicit task). Child participants were instructed to attempt to match the cadence (Explicit task).

Time frame: Session 1 (up to 4 hours)

Phase Locking Value (PLV) - Session 2 Speech Tasks

Adult participants will hear a series of single syllables spoken rhythmically and will be instructed to whisper the syllable "tah" repeatedly while the recording is playing. Child participants did not attend Session 2. The degree of synchronization (how well the participant's whispered syllables match the cadence of the recorded syllables they are listening to) will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals, where 0 is a complete mis-match and a 1 is a perfect match. Adults completed this task twice. For the first test, they were not instructed to attempt to match the cadence (Implicit task). For the second test, they were instructed to attempt to match the cadence (Explicit task).

Time frame: Session 2 (up to 4 hours)

Secondary Outcomes

R Statistic (Resultant Vector Length)

In tapping synchronization (sensorimotor synchronization) research, the R statistic generally refers to the resultant vector length derived from circular statistics, used to quantify the consistency and stability of a participant's tapping relative to a rhythmic stimulus. It ranges from 0 to 1. 0=Complete inconsistency (taps are uniformly distributed). 1=Perfect consistency (all taps occur at the exact same relative phase).

Data from ClinicalTrials.gov

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