Speech Processing in Stuttering

University of Michigan143 enrolled

Overview

This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech. Eligible participants enrolled will complete a variety of computer and speech-based tasks on up to 2 visits.

The study team will update the record to include the secondary identification number once the NIH has released the funds.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

143

Conditions

Stuttering Stuttering, Childhood Stuttering, Adult

Interventions

Speech and non-speech tasksBEHAVIORAL

Participants will complete speech tasks such as listening to and/or producing speech and non-speech sounds.

Eligibility

Sex: ALLMin age: 6 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria (adults who do not stutter): * 18-65 years old * English as primary language * Normal speech, language, hearing, cognition Exclusion criteria: (adults who do not stutter) * Personal or family history of stuttering * Major medical or psychiatric illness Inclusion criteria: (adults who stutter) * Aged 18-65 years * English as primary language * Normal speech, language, hearing, cognition (other than stuttering) * Currently stutters Exclusion criteria: (adults who stutter) * Speech therapy within the past year * Major medical or psychiatric illness Inclusion criteria: (children who do not stutter) * Aged 6 to 17 years * English as primary language * Normal speech, language, hearing, cognition Exclusion criteria: (children who do not stutter) * Personal or family history of stuttering * Major medical or psychiatric illness * Language/motor delay Inclusion criteria: (children who stutter) * Aged 6 to 17 years * English as primary language * Normal speech, language, hearing, cognition (other than stuttering) * Currently stutters Exclusion criteria: (children who stutter) * Major medical or psychiatric illness * Language/motor delay

Locations (2)

University of Michigan

Ann Arbor, Michigan, United States

Michigan State University

East Lansing, Michigan, United States

Outcomes

Primary Outcomes

Phase locking value (PLV) - Session 1 speech tasks

The degree of synchronization will be measured by computing the PLV between subject's produced speech and the heard speech. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals.

Time frame: Session 1 (up to 4 hours)

Phase locking value (PLV) - Session 2 speech tasks

Time frame: Session 2 (up to 4 hours)

Secondary Outcomes

Phase locking value (PLV) - Non-speech tasks

The degree of synchronization will be measured by computing the PLV between subject's produced response and the auditorily presented stimuli. The PLV is a vector with a value between 0 and 1 that reflects the phase difference between two signals.

Time frame: Session 1 (up to 4 hours)

Data from ClinicalTrials.gov

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