Heart failure from myocardial iron deposition is a severe complication for patients with transfusion-dependent beta thalassemia . Increased cardiac iron content impacts the contractility of cardiomyocytes and can also lead to myocarditis, pericarditis, and arrhythmias. The severity of cardiac dysfunction depends on the amount of iron deposited in the myocardium.Echocardiogram is used as noninvasive method to observe heart status. The objective of this study is to evaluate the heart status in patients of Beta Thalassemia from southern China.
Study Type
OBSERVATIONAL
Enrollment
1,200
Echocardiogram and Hematological Analysis
Southern Medical University
Guangzhou, Guangdong, China
RECRUITINGEchocardiogram
Evaluation of heart function in beta thalassemia patients by left ventricular fraction shortening
Time frame: 3 years
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