This study evaluates the viability and safety of no drainage tube placement during transoral endoscopic thyroidectomy vestibular approach in treatment of patients with papillary thyroid carcinoma.
Transoral endoscopic thyroidectomy vestibular approach (TOETVA) is widely used due to its excellent cosmetic effect without scars on the body surface. In prevention of postoperative hemorrhage, a postoperative drainage tube is routinely placed in the surgical area. However, current opinion suggest that under the circumstance of strict and effective intraoperative hemostasis, routine application of drainage tube is unnecessary in conventional open thyroidectomy(COT). The research about drainage placement decision during endoscopic thyroidectomy is scarce currently. This study evaluates the viability and safety of no drainage tube placement during TOETVA on papillary thyroid carcinoma. Patients allocated to the intervention group will implace no drainage tube during TOETVA and those allocated in control group will implace one drainage tube routinely. The incidence of postoperative complications will be evaluated. The time of postoperative hospital-stay and operation time will be evaluated as well. At the same time, blood test results like WBC and CRP will be evaluated 1 day after surgery.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
600
No drainage tube implacement after TOETVA
Second Affiliated Hospital School of Medicine Zhejiang University
Hangzhou, Zhejiang, China
RECRUITINGThe incidence rate of hemorrhage on week 1 after surgery
To evaluate the incidence rate of postoperative hemorrhage (hemorrhage of surgical sites which requires reoperation)
Time frame: 1 week
The incidence rate of infections on week 2 after surgery
To evaluate the incidence rate of infections of surgical sites
Time frame: 2 week
The incidence rate of postoperative hematoma or seroma on week 2 after surgery
To evaluate the incidence rate of postoperative hematoma or seroma
Time frame: 2 week
Pain score on day 1 after surgery
To evaluate the pain score via numerical rating scale on day 1 after surgery. An 11-point numeric scale (NRS 11) with 0 representing no pain and 10 representing worst pain imaginable.
Time frame: 1 day
Body temperature on day 1 after surgery
To evaluate the body temperature on day 1 after surgery.
Time frame: 1 day
WBC on day 1 after surgery
To evaluate the white blood count on day 1 after surgery.
Time frame: 1 day
CRP on day 1 after surgery
To evaluate the C-reaction protein on day 1 after surgery.
Time frame: 1 week
Length of post-operative hospital stay
To evaluate the length of post-operative hospital stay.
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Time frame: 1 week