adding pharmaceutical services to patient care and changing the professional activity of pharmacists from drug-focused to patient-oriented care,in the current study, clinical pharmacists will be assigned to monitor pharmacotherapy regimens, participate in patient care, and cooperate in educating the staff and evaluating care.
During the intervention period, the pharmacist attended daily unit rounds with ICU intensivist with a focus on optimization of antibiotic regimens. Pharmacist consultative services were also available by phone calls 24 hours x 7 days if needed. For every patient surgical prophylactic antibiotic initiated immediately before surgery and continued for 48 hours following surgery. Antibiotic therapy had given as either directed or empiric. Directed therapy was defined as treatment of a documented infection based on culture and sensitivity. Empiric therapy was defined as any antibiotic therapy administered when no documented infection was present, and the patient had clinically suspected infection following surgery. Empiric antibiotic administration was required in majority of our SICU patients. Antibiotics had given after exclusion of allergy by history and intradermal sensitivity test.
Study Type
OBSERVATIONAL
Enrollment
300
antibiotic regimens will be directed by a trained clinical pharmacist recommendation and supported by intensivist.
Alexandria university
Alexandria, Egypt
Antibiotics consumption
consumption will be counted as number of defined daily doses (DDD), expressed as DDD per 100 patient-days
Time frame: 1 year
Average length of stay
the average number of days that patients spent in SICU.
Time frame: 1 year
Mortality rate
The number of deaths of patients admitted to SICU, divided by the number of admissions.
Time frame: 1 year
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