Risk Factors of ICU-acquired Weakness

Second Affiliated Hospital, School of Medicine, Zhejiang University85 enrolled

Overview

We conducted a retrospective study of critical ill patients who used ECMO during their ICU stay. ICU-AW was diagnosed at the time when patients discharged and had a Medical Research Council (MRC) sum score \< 48 out of a maximal score of 60. We divided patients to ICU-acquired weakness group and no ICU-acquired weakness group and compared their clinical characteristics. Baseline characteristics and therapy details were collected from the case report forms and inspection reports. Univariable analysis and logistic regression analysis were used to analyze clinical characteristics of individuals and to find risk factors of ICU-AW.

Study Type

OBSERVATIONAL

Enrollment

Conditions

ICU Acquired Weakness

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Critical ill patients who used extracorporeal membrane oxygenation during their ICU stay. Patients were recruited from the general ICU of the second affiliated hospital of Zhejiang University, between March 2017 to March 2020. Exclusion Criteria: * Patients who was less than 18 years old, had been proven or suspected neurological impairment, using extracorporeal membrane oxygenation less than 24 hours, severe head or spinal cord injury and pregnant woman.

Locations (1)

Xinyi Chen

Hangzhou, Please Select, China

Outcomes

Primary Outcomes

Differences between ICU-acquired weakness in patients receiving extracorporeal membrane oxygenation support

We compared the clinical characteristics between ICU-acquired weakness group and no ICU-acquired weakness group by univariate analysis . Then we used logistic regression analysis and found out differences of ICU-acquired weakness.

Time frame: 1 day

Secondary Outcomes

Frequency of ICU-acquired weakness in in patients receiving extracorporeal membrane oxygenation support

We calculated the prevalence of ICU-acquired weakness on the patients included in our research.