Emerging evidence suggests that regular exercise can complement medical treatment for asthma. Furthermore there are no specific recommendation on how plan exercise training. To the best of current knowledge, there isn't enough evidence of the effect of a strength training in subjects with asthma. Therefore the aim of this study is to evaluate the short and long term effects of a strength and endurance training compared with endurance training alone in subjects with asthma.
To the best of current knowledge, there isn't enough evidence of the effect of a strength training in subjects with asthma. Aim of the study is evaluate the short (after pulmonary rehabilitation) and long term (after 12 months) effects of a strength and endurance training compared with endurance training alone in improving quality of life and disease control in subjects with asthma of Global Initiative for Asthma (GINA) stage from 4 to 5.This is a prospective randomized control trial. Subjects with diagnosis of asthma according to the GINA guidelines admitted to a reference centre for inpatient pulmonary rehabilitation will be randomly assigned to study or control group.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
58
Sessions of strength training added to a standard inpatient multidisciplinary programme
Standard inpatient multidisciplinary programme (including endurance training)
Istituti Clinici Maugeri Pneumologia
Tradate, Lombardy, Italy
asthma related Quality of Life
Asthma Quality of Life Questionnaire (AQLQ). Range 0 (worst) - 7 (best)
Time frame: 4 weeks from enrollment
asthma related Quality of Life
Asthma Quality of Life Questionnaire (AQLQ). Range 0 (worst) - 7 (best)
Time frame: 1 year
Asthma control
Asthma Control Questionnaire (ACQ-6). Range 0 (best) - 6 (worst)
Time frame: 4 weeks from enrollment
Eosinophilic airway inflammation
Fractional Exhaled Nitric Oxide (FeNO),
Time frame: 4 weeks from enrollment
Aerobic capacity
Maximum oxygen capacity (VO2max) assessed by Cardio Pulmonary Exercise Test, (CPET).
Time frame: 4 weeks from enrollment
Quadriceps and biceps strength
Maximal Voluntary isometric Strength (MVS).
Time frame: 4 weeks from enrollment
Quadriceps and biceps strength
Maximal Voluntary isometric Strength (MVS).
Time frame: 1 year
Treatment satisfaction
Global Perceived Effect (GPE) score 1 (best) - 7 (worst)
Time frame: 1 year
Numbers of exacerbations
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
number of exacerbations in the last 12 months.
Time frame: 1 year
Asthma control
Asthma Control Questionnaire (ACQ-6) Range 0 (best) - 6 (worst)
Time frame: 1 year
Eosinophilic airway inflammation
Fractional Exhaled Nitric Oxide (FeNO).
Time frame: 1 year
Aerobic capacity
Maximum oxygen capacity(VO2max) assessed by Cardio Pulmonary Exercise Test (CPET)
Time frame: 1 year