Effect of CPAP vs Control on Nocturnal Dipping in Normotensive Patients With Obstructive Sleep Apnea

Inclusion Criteria: * Newly diagnosed moderate-severe OSA (by standard criteria) * Absence of known hypertension and antihypertensive medication * Office blood pressure \<140/90mmHg * Age 18 - 70 years * Able to provide written, informed consent Exclusion Criteria: * Pregnancy * Previous diagnosis of OSA or previous CPAP treatment * Diagnosis of Diabetes Mellitus * Active treatment for malignancy or severe psychiatric disorder * History of cardiovascular disease or cerebrovascular disease * Moderate or severe chronic kidney disease (CKD) defined as a eGFR of ≤ 44mL/min/1.73m2 * Dipper on ABPM * Morbid obesity, defined as BMI ≥40 * Professional drivers or drivers with a history of road-traffic accident due to sleepiness * Severe excessive daytime sleepiness defined as Epworth sleepiness scale (ESS) \>15