Vagus nerve stimulation (VNS) and paired associative stimulation (PAS) have been shown to have efficacy in improving the results of motor rehabilitation after stroke and spinal cord injury, respectively. Here we will investigate in healthy subjects the synergistic effect of these stimulation modalities on motor-evoked potential (MEP) potentiation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
10
Helsinki University Hospital
Helsinki, Finland
Motor evoked potential (MEP) potentiation
MEPs are responses to transcranial magnetic stimulation recorded from target muscles.
Time frame: 0 minutes after the stimulation protocol
Motor evoked potential (MEP) potentiation
MEPs are responses to transcranial magnetic stimulation recorded from target muscles.
Time frame: 30 minutes after the stimulation protocol
Motor evoked potential (MEP) potentiation
MEPs are responses to transcranial magnetic stimulation recorded from target muscles.
Time frame: 60 minutes after the stimulation protocol
Motor evoked potential (MEP) potentiation
MEPs are responses to transcranial magnetic stimulation recorded from target muscles.
Time frame: 90 minutes after the stimulation protocol
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