D-dimer Prognostic Marker of Cerebral Infarction After Revascularization Procedure

Centre Hospitalier Universitaire, Amiens102 enrolled

Overview

Cerebral infarction is the leading cause of acquired disability in adults. Absence of biological marker used in current practice and identified as a prognostic factor for recovery. D-dimers are degradation products of stabilized fibrin translating an activation of coagulation whatever the cause. Studies have shown that increased D-dimer levels in patients with MI is associated with a higher mortality rate, the link with post-intervention non-revascularization has been demonstrate. The purpose of this project is to search for a correlation between the level of D-dimer and the degree of recovery evaluated by the NIHSS score

Study Type

OBSERVATIONAL

Enrollment

102

Conditions

Cerebral Infarction Cerebral Infarction Recovery

Interventions

blood sampleBIOLOGICAL

D-dimer measurement in blood sample

Outcomes

Primary Outcomes

Correlation between D-dimer concentration and NIHSS score

NIHSS score is based on the clinical neurological examination of the patient. Validated by the scientific community of vascular neurology, among other things in projective clinical research. This score has high inter-observer reproducibility Expressed quantitatively on a scale of 0 to 42 for the NIHSS score A high value of the NIHSS score indicates poor recovery.

Time frame: 3 months

Correlation between D-dimer concentration and NIHSS score

Time frame: 6 months

Correlation between D-dimer concentration and the Rankin score

Rankin Scale collected by the neurologist in consultation 3-6 months post stroke. Expressed quantitatively on a scale of 0 to 6 for the Rankin scale. A high value of the Rankin scale indicates poor recovery.