This is a retrospective non-randomized clinical study of 60 patients total to assess the effects of SARS-CoV-2 infection and the SARS-CoV-2 vaccination. This study will have 2 arms evaluating the epigenomes of patients pre and post-exposure to one of the interventions. The first arm of the study will analyze 40 patients' epigenomes whose DNA methylation was examined pre and post SARS-CoV-2 infection. The second arm of this study is analyzing 20 patients' epigenomes whose DNA methylation was examined pre and post-injection of the SARS-CoV-2 vaccine.
Study Type
OBSERVATIONAL
Enrollment
60
mRNA vaccine for COVID
TruDiagnostic
Lexington, Kentucky, United States
Methylation age clock testing
The DNA clocks that will be used to precisely measure aging is TruAge Biological Age test, which estimates biological age vs. chronological age
Time frame: Change from baseline after COVID-19 infection
Methylation age clock testing
The DNA clocks that will be used to precisely measure aging is TruAge Biological Age test, which estimates biological age vs. chronological age
Time frame: Change from baseline after COVID-19 mRNA vaccination
Overall state of health
Questionnaire assessing overall health
Time frame: Change from baseline after COVID-19 infection
Overall state of health
Questionnaire assessing overall health
Time frame: Change from baseline after COVID-19 mRNA vaccination
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