Ultrasound Evaluation of Abdominal Muscle Thickness During Mechanical Ventilation

Centre Hospitalier de Roanne40 enrolled

Overview

Weakness of respiratory muscles is frequent after several days of mechanical ventilation. Thereby an acquired diaphragm weakness has been demonstrated, linked to an atrophy which may be identified by a decrease of muscle thickness in echography. Weakness of expiratory muscles is also frequent after 7 days of mechanical ventilation, however his cause is not clear: is it present at admission notably in elderly patients, or acquired on mechanical ventilation ? Ultrasound allows to measure the thickness of abdominal muscles which correlates with their strength. This study aims to evaluate with ultrasound the variation of thickness of abdominal muscles after 7 days of mechanical ventilation.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Ventilation Therapy; Complications

Interventions

UltrasoundDEVICE

Ultrasound evaluation of the variation of thickness of abdominal muscles after 7 days of mechanical ventilation.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient affiliated or entitled to a social security plan * Expected duration of mechanical ventilation \> 7 days * Trusted person/relative who has signed a consent to participate in the study Exclusion Criteria: * Patient with a pre-existing neuromuscular pathology * No access to ultrasound Windows (dressing, drainages...) * Patient transferred from another intensive care unit * Patient Under guardianship or curators

Locations (1)

Centre Hospitalier de Roanne

Roanne, France

Outcomes

Primary Outcomes

Thickness of the abdominal muscles (mm)

It is the sum of the thickness of rectus abdominal muscle + external oblique + internal oblique + transverse muscles.

Time frame: Day 7

Secondary Outcomes

Thickness of the rectus abdominal muscles (mm)

Thickness of the rectus abdominal muscles (mm) by ultrasound measurement.

Time frame: Day 7

Thickness of the external oblique abdominal muscles (mm)

Thickness of the external oblique abdominal muscles (mm) by ultrasound measurement

Time frame: Day 7

Thickness of the internal oblique abdominal muscles (mm)

Thickness of the internal oblique abdominal muscles (mm) by ultrasound measurement

Time frame: Day 7

Thickness of the transverse abdominal muscles (mm)

Thickness of the transverse abdominal muscles (mm) by ultrasound measurement

Time frame: Day 7

Diaphragmatic thickness (mm)

Diaphragmatic thickness (mm) measured by ultrasound

Time frame: Day 7

Diaphragmatic thickness (mm)

Diaphragmatic thickness (mm) measured by ultrasound

Time frame: Immediately after the successful extubation of the patient

Number of day with a contraction of the transverse abdominal muscle

Ultrasound search for a contraction of the transverse abdominal muscle during the morning clinical examination each day from D1 to D7

Data from ClinicalTrials.gov

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