The purposes of this study are 1) to explore the association between multi-dimension facial characteristics and the increased risk of coronary artery diseases (CAD); 2) to evaluate the diagnostic efficacy of multi-dimension appearance factors for coronary artery diseases.
Previous study demonstrated the feasibility of using deep learning to detect coronary artery disease based on facial photos. However, several limitations made the algorithm hard to be utilized in clinical practice, including low specificity and lack of external validation. Adding multi-dimension facial characteristics may further increase the algorithm effect. Thus, the investigators designed a single-center, cross-sectional study to explore the association between multi-dimension facial characteristics and CAD and to evaluate the predictive efficacy of multi-dimension appearance factors for CAD. The investigators will recruit patients undergoing coronary angiography or coronary computer tomography angiography. Patients' baseline information and multi-dimension facial images will be collected. The investigators will train and validate a deep learning algorithm based on multi-dimension facial photos.
Study Type
OBSERVATIONAL
Enrollment
460
No intervention
Fuwai hospital
Beijing, Beijing Municipality, China
Area under receiver operating curve (AUC)
Area under receiver operating curve of algorithm assessed in test group
Time frame: At the end of enrollment (1 mouth)
Sensitivity of algorithm
Sensitivity of algorithm assessed in test group
Time frame: At the end of enrollment (1 mouth)
Specificity of algorithm
Specificity of algorithm assessed in test group
Time frame: At the end of enrollment (1 mouth)
Positive predictive value (PPV)
PPV of algorithm assessed in test group
Time frame: At the end of enrollment (1 mouth)
Negative predictive value (NPV)
NPV of algorithm assessed in test group
Time frame: At the end of enrollment (1 mouth)
Diagnostic accuracy rate
Diagnostic accuracy rate of algorithm assessed in test group
Time frame: At the end of enrollment (1 mouth)
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