Study on the Effect of Selenium Supplementation on the Structure and Function of Autoimmune Thyroiditis

Beijing Chao Yang Hospital30 enrolled

Overview

To evaluate the effects of exogenous selenium supplementation on autoimmune thyroiditis.

In patients with autoimmune thyroiditis， investigators compared changes in thyroid function, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody, thyroid magnetic resonance T1-mapping values and metabolic indicatorsfrom baseline to the end of treatment (12 weeks)

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Selenium

Interventions

SeleniumDRUG

selenium 100ug ，take it orally twice daily

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Men or women between the ages of 18 and 75 * Clinical diagnosis of autoimmune thyroiditis, serum TPOAb and TGAB positive * Thyroid function is normal, and no drugs affecting thyroid function such as Umetole and Serge have been used Exclusion Criteria: * The contraindications indicated in the Chinese instructions of the drug * Hypothyroidism, hyperthyroidism * Liver function impairment * Renal function impairment * Claustrophobia * Mental disorders

Locations (1)

Beijing Chao-Yang Hospital, Capital Medical University

Beijing, Beijing Municipality, China

RECRUITING

Outcomes

Primary Outcomes

anti-thyroglobulin antibody changes

Changes from baseline and 3 months during follow-up

Time frame: Changes from baseline and 3 months during follow-up

T1-mapping values of Thyroid MRI

Changes from baseline and 3 months during follow-up

Time frame: Changes from baseline and 3 months during follow-up

Central Contacts

Jia Liu, MD

CONTACT

861085231710 liujia0116@126.com

Xiaomeng Sun

CONTACT

861085231711 beijingxiaosun2010@163.com

Data from ClinicalTrials.gov

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