The alternatives to the combination of Fluoroquinolone and Rifampicin in prosthetic joint infections (PJI) caused by staphylococcus are currently unclear. Clindamycin is prescribed as dual therapy in this indication, and provides many advantages. We conducted a multicenter retrospective observational study evaluating the efficacy and safety of Clindamycin in prosthetic joint infections due to staphylococcus between January 2013 and December 2019.
Study Type
OBSERVATIONAL
Enrollment
120
CHU de Brest
Brest, France
Failure of Clindamycine
New diagnosis of PJI at the same site, caused by the same microbial agent
Time frame: within 2 years of the diagnosis (within one year for patients diagnosed in December 2019)
Safety of Clindamycin
Safety of Clindamycin in the treatment of PJI
Time frame: During the treatment and 6 month after
Correlation between failure of Clindamycin and blood level of Clindamycin
Time frame: within 2 years of the diagnosis (within one year for patients diagnosed in December 2019)
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