The aim of this study is to investigate the effect of a six-week period personalised food intervention with prebiotic supplementation on intense exercise performance in healthy, recreationally active adults.
The study conforms to a randomized, single-blinded, placebo-controlled parallel study design. a prebiotic supplement will be selected based on a participants gut microbiota. 1 sachet of prebiotic or placebo will be given twice a day over a period of 6 weeks. Before the start of the study, a VO2max test will be performed. Subjects will bring faecal samples which is collected at home. A time to exhaustion of approximately 80% of their VO2max will be performed at baseline and after the 6 weeks intervention period.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
34
Maastricht University
Maastricht, Limburg, Netherlands
RECRUITINGTime to Exhaustion
Time on cycle ergometer until exhaustion
Time frame: From baseline to end of the study (up to max 45 days)
Gut microbiota composition
Composition of the gut microbiota by faecal sample analysis
Time frame: From baseline to end of the study (up to max 45 days)
Plasma short chain fatty acids
Short chain fatty acids in plasma
Time frame: From baseline to end of the study (up to max 45 days)
Blood glucose
Fasted blood glucose
Time frame: From baseline to end of the study (up to max 45 days)
Insulin
Fasted insulin
Time frame: From baseline to end of the study (up to max 45 days)
Intestinal permeability by sugar test
Intestinal permeability measured by a sugar drink test
Time frame: From baseline to end of the study (up to max 45 days)
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