Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous

North Estonia Medical Centre100 enrolled

Overview

Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous is a prospective randomized controlled trial comparing 24 hour intravenous antibacterial therapy to 24 hour oral antibacterial therapy after surgery in complicated appendicitis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Acute Appendicitis Acute Appendicitis With Rupture Acute Appendicitis Without Peritonitis Acute Appendicitis With Appendix Abscess Appendicitis; Perforation

Interventions

Oral versus intravenous administration of antibacterial treatmentOTHER

Mode of administration of antibacterial treatment

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Patients diagnosed with acute appendicitis and are candidates for laparoscopic appendectomy. Exclusion Criteria: Patients with compromised immune system (HIV, diabetes), ongoing or completed radio-chemotherapy in past 5 years, prosthetic heart valve, vascular prosthesis, pregnancy.

Locations (1)

North Estonia Medical Centre

Tallinn, Estonia

RECRUITING

Outcomes

Primary Outcomes

Infectious complications

Time frame: 30 days

Central Contacts

Edgar Lipping, MD

CONTACT

6171520 edgar.lipping@regionaalhaigla.ee

Sten Saar, MD, PhD

CONTACT

6171520 sten.saar@regionaalhaigla.ee

Data from ClinicalTrials.gov

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