Adequate bowel preparation is critical for successful colonoscopy and a large volume of PEG was required for bowel preparation in patients undergoing colonoscopy. The investigators conducted a a prospective, randomized, controlled study to compare low dose of oral magnesium sulfate solution with high dose PEG. The investigators found that patients who took low dose of oral magnesium sulfate solution had similar bowel preparation quality to patients who took PEG,but accompanied with fewer adverse events and better tolerance.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
1,174
purgative for bowel preparation
purgative for bowel preparation
Endoscopic center, Xijing Hospital of Digestive Diseases
Xi’an, Shanxi, China
Department of Gastroenterology, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital,
Beijing, China
The rate of patients with adequate bowel preparation
Defined by each segmental BBPS≥2
Time frame: 1 year
The rate of adenoma detection
The proportion of participants with at least one adenoma in each group
Time frame: 1 year
the numbers of patients with adverse events
eg. Vomiting, nausea, abdominal pain
Time frame: 1 year
The cecal intubation rate
The rate of colonoscopy reaching the cecum
Time frame: 1 year
The time of Cecal intubation
the time between the intubation and visualization of any of the following anatomic landmarks: ileocecal valve, appendiceal orifice, or terminal ileum
Time frame: during procedure
the time during Withdrawal phage
the inspection time from cecum to rectum
Time frame: during procedure
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