Comparison of AOCT and AOPT for the Treatment of Medial Large Cystic OLT

Peking University Third Hospital46 enrolled

Overview

Autologous osteoperiosteal transplantation using tissue harvested from the iliac crest is used to treat large cystic osteochondral lesions of the talus. This study is to compare clinical and radiological outcomes between patients undergoing AOPT and those undergoing AOCT for large cystic OLTs.

From March 2015 to March 2018, 23 patients who underwent AOPT and 23 patients who underwent AOCT to treat large cystic OLTs (\>10mm) were retrospectively evaluated. For comparability, the two groups were matched based on their demographics, including sex, age, body mass index, side of injury, follow-up period, and the preoperative cyst volume. Clinical outcomes were assessed using the visual analog scale (VAS), the American Orthopaedic Foot \& Ankle Society (AOFAS) score, and the Tegner score. Donor-site morbidity was recorded according to the symptoms, including pain, stiffness, swelling and discomfort. Radiological outcomes were evaluated using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score, and the International Cartilage Repair Society (ICRS) score was obtained during second-look surgery.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Osteochondral Lesions of the Talus

Interventions

AOPTPROCEDURE

The Osteochondral Autograft Transplant System (Arthrex) was used to create donor plugs. Osteoperiosteal grafts were harvested from the ipsilateral anterior superior iliac spine.

AOCTPROCEDURE

Osteochondral grafts were harvested from the non-weight-bearing zone of the ipsilateral anterolateral distal femur.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * presence of medial large cystic OLTs (\>10 mm in diameter) confirmed by preoperative magnetic resonance imaging (MRI) * patients who underwent either primary AOPT or AOCT Exclusion Criteria: * small cystic OLTs * ankle osteoarthritis * ankle pigmented villonodular synovitis * prior surgery on the ipsilateral ankle * injuries or relevant trauma to the affected ankle after surgery

Outcomes

Primary Outcomes

MOCART

the Magnetic Resonance Observation of Cartilage Repair Tissue score

Time frame: two years after sugery

Secondary Outcomes

VAS

the visual analog scale

Time frame: pre-surgery, two years after sugery

Tegner

the Tegner score

Time frame: pre-surgery, two years after sugery

AOFAS

American Orthopaedic Foot \& Ankle Society score

Time frame: pre-surgery, two years after sugery

ICRS

the International Cartilage Repair Society score

Time frame: one year after sugery

Data from ClinicalTrials.gov

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