During pregnancy many physiological changes and adaptations occur.Hormonal, hematological and hemodynamic changes are responsible for most of the ocular adaptations.We are planning to compare the choroid and retinal blood flow values and choroidal thickness of pregnant women and healthy non pregnant women with optical coherence tomography and optic coherence tomography angiography
During pregnancy many physiological changes and adaptations occur such as pulmonary, renal, endocrinological, haematological and visual system changes are happening. In previous studies, retinal and choroidal pregnancy-related changes in blood flow and choroidal thickness have been demonstrated. Optical coherence tomography angiography (OCTA) detects the contrast of motion in the blood flow, detecting the capillary of the retina and choroid. It is a new functional method that visualizes the retinal networks and outer retina without using dyes.It is a non-invasive method that provides volumetric angiography information. In this study evaluation of the variability of choroidal and retinal blood flow changes and choroidal thickness, between trimesters of pregnancy and the non-pregnant control group is planned. Choroid and Retinal Blood Flow Values and Choroidal thickness in 41 pregnant women in the first trimester and it would be repeated at second and third trimesters. We compare measured values between trimesters and 45 healthy non-pregnant women.
Study Type
OBSERVATIONAL
Enrollment
86
Optical coherence tomography optical coherence tomography angiography
Akdeniz University Hospital
Antalya, Turkey (Türkiye)
Choroidal thickness
Choroidal thickness is measured by optical coherence tomography
Time frame: 40 weeks
Retinal thickness
Retinal thickness is measured by optical coherence tomography
Time frame: 40 weeks
Foveal avascular zone(FAZ) area measurement
FAZ area is measured by optical coherence tomography anjiography
Time frame: 40 weeks
Retinal vascular density
% of retinal vascular density is measured by optical coherence tomography angiography
Time frame: 40 weeks
Retinal nerve fiber layer thickness
Retinal nerve fiber layer thickness (um) is measured by optical coherence tomography
Time frame: 40 weeks
Ganglion cell layer measurement
Ganglion cell layer measurement is measured by optical coherence tomography
Time frame: 40 weeks
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