People with dementia shows a decline in cognition, such as memory, executive function (EF), language, attention, and spatial orientation that is significant enough to interfere with the independence and daily functioning. Previous studies reported that multicomponent exercise improved EF in people with mild cognitive impairment and independence of ADL in those with Alzheimer's disease. However, few studies investigated whether multicomponent exercise improved EF, memory, and ADL in people with dementia. Therefore, the purposes of this study are to examine 1) the effect of multicomponent exercise on EF, memory, and ADL in people with mild to moderate dementia; 2) the correlation between change in EF and ADL; 3) the correlation between change in memory and ADL.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
52
The intervention is a 60-minute session, 3 times/week, totaling 9 weeks. Multicomponent exercise included strengthening, balance training, aerobic dance, and stretching
The intervention is a 60-minute session, 3 times/week, totaling 9 weeks. Video home exercise included four limbs mobility exercise, stretching, strengthening, and aerobic exercise
Mini-Mental State Examination
It is a 30-point questionnaire that is used extensively in clinical and research settings to measure cognitive impairment. Higher scores mean a better outcome.
Time frame: Change from baseline at 9 week
Chinese version of Verbal learning test
It is a 9-point measurement to evaluate memory. Higher scores mean a better outcome.
Time frame: Change from baseline at 9 week
Chinese version of Stroop color and word test
It is a measurement to evaluate inhibition control.
Time frame: Change from baseline at 9 week
Digit span test
It is a measurement to evaluate working memory.
Time frame: Change from baseline at 9 week
Trail making test - Chinese version
It is a measurement to evaluate cognitive flexibility.
Time frame: Change from baseline at 9 week
Barthel index
It is a 100-point ordinal scale used to measure performance in activities of daily living. Higher scores mean a better outcome.
Time frame: Change from baseline at 9 week
Instrumental activities of daily living (IADL) scale
It is a 24-point ordinal scale used to measure performance in instrumental activities of daily living. Higher scores mean a better outcome.
Time frame: Change from baseline at 9 week
Chinese version of Quality of Life in Alzheimer Disease Scale
It is a measurement to evaluate quality of life. The scale scores range from 13 to 52, with higher scores indicating greater quality of life.
Time frame: Change from baseline at 9 week
Time up and go test
It is a test to evaluate functional mobility.
Time frame: Change from baseline at 9 week
30-second chair stand test
It is a test to evaluate muscle strength.
Time frame: Change from baseline at 9 week
6-minute walk test
It is a test to evaluate endurance.
Time frame: Change from baseline at 9 week
Berg Balance Scale
It is a tool to evaluate balance. It is a 14 item list with each item consisting of a five-point ordinal scale ranging from 0 to 4, with 0 indicating the lowest level of function and 4 the highest level of function.
Time frame: Change from baseline at 9 week
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