Although whole body vibration (WBV) is mainly designed to promote neuromuscular function, however, because of its vibration characteristics, whether it can provide additional effects on the sputum clearance for chronic obstructive pulmonary (COPD) disease patients, thereby improving the quality of life, and exercise capacity is still unknown.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
26
Subjects received the interventions twice a week for 8 weeks. HFCWO+WBVT group received additional 30 minutes WBVT treatment. In every WBVT session, three rounds of 3 minutes of vibration (amplitude: 2 mm; frequency: 20 Hz) were provided, with a 60-second rest between rounds.
Subjects received the interventions twice a week for 8 weeks. The HFCWO was delivered by a respiratory therapist using a percussive vest at 10-13 Hz oscillating frequency and at a pressure setting of 2 cm H2O. The treatment duration was 25 minutes, and the participants remained in a sitting position.
Kaohsiung Medical University Hospital
Kaohsiung City, Taiwan
FVC
forced vital capacity tested in pulmonary function test (Liters)
Time frame: 8 weeks
FEV1
forced expiratory volume in 1 second in pulmonary function test (Liters)
Time frame: 8 weeks
FEV1/FVC
forced expiratory volume in 1 second divided by forced vital capacity in pulmonary function test (%)
Time frame: 8 weeks
FVC(% pred)
percentage of predicted FVC value (% pred)
Time frame: 8 weeks
FEV1(% pred)
percentage of predicted FEV1 value (% pred)
Time frame: 8 weeks
6 min walk distance
the distance walked in 6 minutes (m)
Time frame: 8 weeks
Predicted distance
percentage of the predicted 6 minute walk test distance (%pred)
Time frame: 8 weeks
Distance-Saturation Product (DSP)
the product of distance walked and lowest oxygen saturation during the 6-min walk test (m%)
Time frame: 8 weeks
1 min STST
the number of repetitions performed in the 1-min sit-to-stand test (rep.)
Time frame: 8 weeks
5-rep STST
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the complete time for the 5-repetition sit-to-stand test (sec)
Time frame: 8 weeks
Muscle strength test1
Maximal force output for biceps femoris muscle (lbs)
Time frame: 8 weeks
Muscle strength test2
maximal force output for quadriceps muscle (lbs)
Time frame: 8 weeks
Sputum self-assessment scale
questionnaire of sputum volume, it contained three items (0-25 mL/d, 25-50 mL/d, and 50-100 mL/d) as a checklist
Time frame: 8 weeks
X-ray score
the evaluation of the chest radiography based on the sputum impaction score, scores ranging from 0 to 18. A decrease in score represented an improvement in sputum in each area.
Time frame: 8 weeks
modified Medical Research Council (mMRC)
questionnaire of dyspnea, scores ranging from 0 (low degree of dyspnea) to 4 (high degree of dyspnea)
Time frame: 8 weeks
chronic obstructive pulmonary disease assessment test (CAT)
questionnaire of COPD symptoms, scores ranging from 0 to 40, higher scores indicating more severe impact of COPD on their life
Time frame: 8 weeks
Saint George Respiratory Questionnaire (SGRQ)
questionnaire of overall health, daily life, and perceived well-being, scores ranging from 0 (no health impairment) to 100 (maximum health impairment)
Time frame: 8 weeks