Single-dose Mass Balance Recovery and Metabolite Profile and Identification of 14C-XEN1101

Key Inclusion Criteria: * Body mass index (BMI) of 18.0 to 32.0 kg/m2 * Must be willing and able to communicate and participate in the whole study * Provide written informed consent * Adhere to the specified contraception requirements Key Exclusion Criteria: * Subjects who have received any investigational medicinal product (IMP) in a clinical research study within 90 days * Evidence of any current infection or an infection within 14 days before study drug administration * History of any drug or alcohol abuse in the past 2 years * Subjects with pregnant or lactating partners * Radiation exposure, including that from the present study, excluding background radiation but including diagnostic x-rays and other medical exposures, exceeding 5 millisievert (mSv) in the last 12 months or 10 mSv in the last 5 years. No occupationally exposed worker, as defined in the Ionising Radiation Regulations 2017, shall participate in the study * Participation in a clinical trial involving administration of radiolabelled compound(s) within 180 days of the planned dosing date of this study * Clinically significant abnormal clinical chemistry, haematology, coagulation or urinalysis. Subjects with Gilbert's Syndrome will be excluded. * Confirmed positive drugs of abuse test result * Positive hepatitis B surface antigen (HBsAg), hepatitis C virus antibody (HCV Ab) or human immunodeficiency virus (HIV) antibody results * History of clinically significant cardiovascular, renal, hepatic, dermatological, chronic respiratory or gastrointestinal disease, neurological or psychiatric disorder * Donation of blood or plasma within the previous 3 months or loss of greater than 400 mL of blood