Evaluation of T2, T3 Sympathectomy for Postmastectomy Pain Syndrome by Pulse Oximeter

National Cancer Institute, Egypt54 enrolled

Overview

The aim of the study is to compare the efficacy of T2, T3 sympathetic block using thermal radiofrequency versus chemical neurolysis in postmastectomy pain syndrome using perfusion index derived from pulse oximetry.

Postmastectomy pain is a chronic pain condition with neuropathic nature. Several drugs and methods are used for its management. This study was designed to compare the efficacy of both thermal radiofrequency and chemical neurolysis in management of postmastectomy pain through using perfusion index derived from pulse oximetry.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Analgesia

Interventions

Thermal RadiofrequencyPROCEDURE

Radiofrequency lesioning at level of T2 and T3 using 80°c for 120 seconds

Chemical NeurolysisPROCEDURE

injection of 1.5 ml of the chemical neurolytic agent (phenol in saline 8%) at each level

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Female patients with postmastectomy pain syndrome * ≥ Age 18 years * ASA II-III Exclusion Criteria: * patient refusal * coagulation defects * abnormal kidney or liver functions * local infection at site of injection * bone metastases * severe cardiorespiratory disease

Locations (1)

Walaa Y Elsabeeny

Cairo, Egypt

Outcomes

Primary Outcomes

Visual analogue score

minimum score 0 and maximum score 10

Time frame: up to 24 weeks

Secondary Outcomes

Perfusion index trend

measuring the change in perfusion index in the ipsilateral limb after the procedure compared to pre-procedural

Time frame: procedure time

Opioid consumption

average opioid consumption

Time frame: up to 24 weeks

Data from ClinicalTrials.gov

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