Development and Validation of a Prediction Model for Refeeding Syndrome in ICU Patients Undergoing Enteral Nutrition Patients

Second Affiliated Hospital, School of Medicine, Zhejiang University553 enrolled

Overview

This study intends to strengthen the discussion on the risk factors of RFS in critically ill patients, and construct an RFS risk prediction model which is easy for clinical medical staff to use and has a high sensitivity and specificity; In order to help medical staff to identify the high-risk groups of RFS in critically ill patients efficiently and accurately, and take targeted care and treatment for patients, so as to reduce the adverse consequences of RFS on critically ill patients.

Study Type

OBSERVATIONAL

Enrollment

553

Conditions

Development and Validation of a Prediction Model for Refeeding Syndrome in ICU Patients Undergoing Enteral Nutrition

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * (1) Age ≥18 years old; (2) Patients with mechanical ventilation; (3) First admission to ICU； (4) The time of receiving enteral nutrition support in ICU was ≥ 3 days. Exclusion Criteria: * (1)Ppregnant women or lactating patients;(2) Patients with incomplete information;(3) There are other risk factors leading to hypophosphatemia, such as continuous hemodialysis , hyperphosphatemia treatment,Parathyroid gland resection was performed within 3 months.

Locations (1)

Outcomes

Primary Outcomes

Occurrence of RFS

Occurrence of RFS：Within 72 hours after feeding serum phosphorus \< 0.0.87mmol/L, or from the baseline levels drop \> 0.16% or drop \> 30%;And (or) hypokalemia, hypomagnesemia, hypocalcemia and corresponding clinical symptoms.

Time frame: from December 1, 2019 to October 31, 2020