1\. To research the current situation of severe infection in children in China, and to investigate the incidence, prognosis and disease burden of severe infection in children in different regions of China. 2. Establish the risk prediction model and diagnosi model of severe infection in children, and verify the accuracy of the model in multi-center; 3. To study the effectiveness and safety of different treatments in real diagnosis and treatment, and to evaluate the efficacy of subgroups under different ages and high risk factors.
1.Children between 0 and 18 years old. 2.Severe pneumonia and/or sepsis.Patients were included who meet the guidline for diagnosis and treatment of community-acquired pneumonia in Children (2019) issued by the National Health Commission of the people's Republic of China and/or who meet the International Guide to the 2020 campaign to Save sepsis: management of septic shock and sepsis-related organ dysfunction in children. 3.notifiable infectious diseases.4.The researcher believes that he is not suitable to participate in other situations in this study.5.Participants in other clinical trials in the same period.
Study Type
OBSERVATIONAL
Enrollment
5,000
This is a prospective observational study and does not include interventions.
Children's Hospital of Fudan University
Shanghai, Shanghai Municipality, China
RECRUITINGsurvival rate
The survival rate of children in 28 days after their discharged from PICU
Time frame: within 28 days after they discharged from PICU
length of stay in PICU
Time from PICU admission to discharge
Time frame: within 28 days after they discharged from PICU
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