This randomized trial will use a Negative Pressure Wound Therapy device or standard wound closure, in participants with gastrointestinal neoplasms, to measure the rate of surgical site infections
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Enrollment
290
Negative Pressure Wound Therapy is a single use NPWT that produces a negative pressure at -80 mmHg. Participants will have their fascia and skin closed in the same manner as the control arm participants, and will wear the NPWT dressing for 7 days after surgery.
Moffitt Cancer Center
Tampa, Florida, United States
Surgical Site Infection - Superficial Incisional
Investigators will measure rate of Surgical Site Infection (SSI) of participants who received Superficial Incisions.
Time frame: 30 days post operation
Surgical Site Infection - Deep Incisional
Investigators will measure rate of Surgical Site Infection (SSI) of participants who received Deep Incisions.
Time frame: 30 days post operation
Surgical Site Infection - Organ/Space Incisional
Investigators will measure rate of Surgical Site Infection (SSI) of participants who received Organ/Space Incisions.
Time frame: 30 days post operation
Return to Intended Oncologic Therapy (RIOT)
Investigators will measure number of participants who returned to their intended oncologic therapy
Time frame: Up to 12 months after surgery
Time to Initiation of Planned Oncologic Therapy
Investigators will measure time to initiation planned therapy from the surgery date to initiation date of planned oncologic therapy
Time frame: Up to 12 months after surgery
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