The Correlation of Preoperative Measurement Parameter on the Predicting of Visual Outcomes Among Patients With Idiopathic Macular Holes

Second Affiliated Hospital, School of Medicine, Zhejiang University60 enrolled

Overview

This study retrospectively analyzed the relationship between the preoperative optical coherence tomography(OCT) and optical coherence tomography angiography(OCTA) software related parameters of patients with idiopathic macular hole, the patient's own clinical data and the best corrected visual acuity (BCVA) for at least one month after surgery.

After Pars plana vitrectomy combined with removal of the internal limiting membrane (ILM) and air filling, it can not only promote the closure of the macular hole in patients with idiopathic macular hole, but also improve the visual acuity of the affected eye. There are various studies to predict the visual acuity of patients after surgery recovery, but due to many factors that affect the effect of macular hole surgery, the improvement of visual acuity after retinal surgery varies greatly in different eyes. As a new type of ophthalmology device, OCTA plays an important role in measuring the size of the hole and the changes of retinal capillaries. Therefore, this study intends to calculate patient parameters based on OCT and OCTA equipment. Statistical software was used to analyze the relationship between each parameter and the best corrected visual acuity (BCVA) for at least one month after surgery.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Macular Holes

Interventions

No interventionOTHER

No intervention

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * idiopathic MHs, the MH is closed ,and follow-up for at least 1 month after vitrectomy. Exclusion Criteria: * High myopia (≥6 diopters,AL≥26.5mm), increased intraocular pressure (IOP, \>21 mm Hg) or glaucoma, severe cataract, severe corneal disease，severe systemic conditions that prevent surgery, and history of ocular trauma, intraocular inflammation, retinal vascular disease, or previous ocular surgery

Locations (1)

Department of Ophthalmology, The Second Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

RECRUITING

Outcomes

Primary Outcomes

Macular hole status

macular hole status (open, flat open or closed)

Time frame: at 1 month after surgery

MLD of macular hole

Calculation of minimum liner diameter of macular hole with optical coherence tomography angiography

Time frame: Before surgery

BD of macular hole

Calculation of base diameter of macular hole with optical coherence tomography angiography

Time frame: Before surgery

Choroidal hypertransmission width of macular hole

Calculation of Choroidal hypertransmission width of macular hole with optical coherence tomography angiography

Time frame: Before surgery

Horizontal ellipsoid band missing diameter of macular hole

Calculation of Horizontal ellipsoid band missing diameter of macular hole with optical coherence tomography angiography

Time frame: Before surgery

Baseline best-corrected visual acuity

best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis

Time frame: Before surgery

best-corrected visual acuity at 1 month

best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis

Time frame: at 1 month after surgery

best-corrected visual acuity at 2 months

Central Contacts

Zhiyong Zhang, docter

CONTACT

13968059392 zhangziyongnet@163.com

Data from ClinicalTrials.gov

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best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis

Time frame: at 2 months after surgery

best-corrected visual acuity at 3 months

best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis

Time frame: at 3 months after surgery

best-corrected visual acuity at 4 months

best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis

Time frame: at 4 months after surgery

best-corrected visual acuity at 5 months

best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis

Time frame: at 5 months after surgery

best-corrected visual acuity at 6 months

best-corrected visual acuity were gauged with EDTRS charts,recorded in decimals and was converted to logarithm of the minimum angle of resolution units for statistical analysis

Time frame: at 6 months after surgery

FAZ area of macular hole

Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography

Time frame: Before surgery

FAZ area of macular hole at 1 month

Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography

Time frame: at 1 month after surgery

FAZ area of macular hole at 2 months

Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography

Time frame: at 2 months after surgery

FAZ area of macular hole at 3 months

Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography

Time frame: at 3 months after surgery

FAZ area of macular hole at 4 months

Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography

Time frame: at 4 months after surgery

FAZ area of macular hole at 5 months

Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography

Time frame: at 5 months after surgery

FAZ area of macular hole at 6 months

Calculation of foveal avascular zone (FAZ) area of macular hole with optical coherence tomography angiography

Time frame: at 6 months after surgery

CRT of macular hole