This study aimed to evaluate the levels of interleukin 10, interleukin 6, interleukin 32 and tumor necrosis factor-alpha (TNF-α) in saliva of children with early childhood caries.
Fifty six children ( 28 with early childhood caries and 28 without early childhood caries ; age range 3-6 years) will be recruited for the study. Probing pocket depth (PPD), gingival index (GI) and plaque index (PI) will be recorded and saliva samples will be collected. Interleukin-32, Interleukin-10, Interleukin-6 and TNF-α will be analyzed in saliva samples by ELISA.
Study Type
OBSERVATIONAL
Enrollment
58
Enzim linked immunoabsorbant assay
Sultan KELEŞ
Aydin, Turkey (Türkiye)
IL-32
Interleukin- 32 level
Time frame: Baseline
IL-10
Interleukin- 10 level
Time frame: Baseline
IL-6
Interleukin- 6 level
Time frame: Baseline
Tnf-Alpha
Tnf-alpha level
Time frame: Baseline
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