According to ESGO-ESTRO-ESMO guidelines, pelvic Sentinel lymph node detection is suitable for lymph node staging in endometrial carcinoma of the uteri. Nonetheless, a learning curve is mandatory to ensure the surgical quality of the sampling. The aim of the study is to assess the success of sentinel lymph node detection according to SHREC-Trial surgical strategy.
Introduction: According to ESGO-ESTRO-ESMO guidelines, pelvic Sentinel lymph node detection is suitable for lymph node staging in endometrial carcinoma of the uteri. The aim of the study is to assess the success of sentinel lymph node detection according to SHREC-Trial surgical strategy. Patients and Method: All patients presenting with early FIGO stage and low, intermediate, high intermediate or high risk endometrial carcinoma will be prospectively enrolled. Sentinel lymph node mapping will be performed using laparoscopic approach and cervical Indocyanine Green injection. Based on the surgical algorithm for detection of pelvic sentinel lymph node in endometrial cancer from Persson and coll., we designed a study with a target of 70% to 90% of bilateral detection rate . Thirty patients will be included over 18 months.
Study Type
OBSERVATIONAL
Enrollment
30
CHRU de Brest
Brest, France
Bilateral node detection rates
target = 70% to 90%
Time frame: Day 0 (during surgery)
sentinel nodes
number of sentinel nodes collected
Time frame: Day 0 (during surgery)
Salvage operations in case of GS failure
Number of salvage operations
Time frame: Day 0 (during surgery)
adverse events
Per and post operative adverse events according to Clavine Dindo Classification
Time frame: Day 30
factors for detection failure
Time frame: Day 0 (during surgery)
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