To determine the prevalence and the prognosis in a corhort of patients with familial hypercholesterolemia (FH).
This study aims to achieve the following goals through prospective cohort study and statistical analysis: (1) to determine the prevalence of familial hypercholesterolemia (FH) in healthy people with hypercholesterolemia.(2) Compared with non FH population, the relative risk of atherosclerotic cardiovascular disease (ASCVD) in FH patients in China was calculated, and the risk prediction model of ASCVD in FH patients was constructed by using biochemical results, imaging data, biomarkers and other indicators.(3) To evaluate the benefits of different lipid-lowering strategies for FH patients in China.(4) To analyze the gene carriers of FH patients in China.
Study Type
OBSERVATIONAL
Enrollment
318
Among the selected patients with hyperlipidemia, those who met the diagnostic criteria of FH were included in the study cohort as FH group.
Number of participants with atherosclerotic cardiovascular disease (ASCVD) events
1\) Fatal or non-fatal myocardial infarction; 2) Fatal or non-fatal ischemic stroke; 3) Coronary artery revascularization; 4) Peripheral artery revascularization; 5) Cardiogenic death
Time frame: 2 years from enrollmet
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