Spanish Registry of Esophagogastric Cancer

Fundación Sociedad Española de Oncologia Médica10,000 enrolled

Overview

This study aims to development of a database through a web page for epidemiological and clinical research purposes that is accessible to members of the AGAMENON - SEOM group that guarantees a rigorous collection, exploitation and analysis of the data and information contained, increases the knowledge of esophageal and stomach cancer in order to optimize the management, treatment and evolution of patients, the possibility of comparing variables with those of other series or groups, and promotes the quality of scientific publications.

Patient data will be collected from medical records retrospectively.

Study Type

OBSERVATIONAL

Enrollment

10,000

Conditions

Esophageal Cancer Gastric Cancer

Interventions

SurgeryPROCEDURE

Surgery

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patient (≥18 years) diagnosed with carcinoma of the esophagus, gastroesophageal junction and stomach, including all histologic subtypes, with or without erbB2 overexpression (and tumors in which this data is unknown). * Follow-up of at least 3 months with clinical information during this period, exempting patients with early death from any cause. Exclusion Criteria: * A patient for whom, for whatever reason, the information necessary to complete the database cannot be known or obtained.

Locations (38)

Hospital General Universitario de Alicante

Alicante, Alicante, Spain

RECRUITING

Hospital General Universitario de Elche

Elche, Alicante, Spain

RECRUITING

Hospital General Universitario de Elda

Elda, Alicante, Spain

RECRUITING

Hospital Universitario Reina Sofia

Córdoba, Andalusia, Spain

Outcomes

Primary Outcomes

Diagnostic and therapeutic approach

To evaluate survival (time in months) according to treatment of esophagogastric cancer in all stages, patients, and contexts.

Time frame: Up to 12 months

Secondary Outcomes

Epidemiological profiles

To know the epidemiological profiles of esophagogastric cancer in Spain: temporal and regional trends, morbidity, and mortality.

Time frame: Up to 12 months

Risk factors

To study risk factors associated with each subtype of esophagogastric cancer and localization.

Time frame: Up to 12 months

Pathological features

To evaluate the pathological features (TNM, grade, histological response) The TNM is measured with the American Joint Committee on Cancer (AJCC) staging system. The grade is classified with the WHO scale. Histological response is measured with Becker classification.

Time frame: Up to 12 months

Clinical and diagnostic approach

To know the diagnostic approch according to the center, type of studies performed: endoscopy, CT, echoendoscopy and/or PET/CT. From these studies it will be collected whether they have been carried out and where they visualise tumour. The use of scales and measurements is therefore not appropriate.

Time frame: Up to 12 months

Treatments adjusted to prognostic variables

To compare treatments adjusted to prognostic variables and baseline characteristics.

Time frame: Up to 12 months

Validate and compare prognostic models

To validate and compare the three prognostic models for advanced esophagogastric adenocarcinoma: The Royal Marsden Hospital index (Chau et al, 2004), and the models of Kim (2008) and Lee (2007), in a real sample of patients based on daily clinical practice.

Time frame: Up to 12 months

Prognostic factors

To analyze the prognostic factors in this population and build a predictive and/or prognostic model.

Time frame: Up to 12 months

Create and validate a predictive model

To create and validate a predictive model of early mortality.

Time frame: Up to 12 months

Spanish Registry of Esophagogastric Cancer

Overview

Conditions

Interventions

Eligibility

Locations (38)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts