Shear-wave Elastography Compared to Respiratory Function Testing

Mayo Clinic24 enrolled

Overview

The purpose of this study is to evaluate the relationship between transdiaphragmatic pressure (Pdi) and diaphragm shear-wave elastography (SWE) during state-of-the-art respiratory muscle testing including volitional efforts (e.g., maximal inspiratory pressure, maximal expiratory pressure, Valsalva maneuver), as well as maximal phrenic nerve stimulation.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Respiratory Function Loss Respiratory Complication

Interventions

Shear-wave elastographyDIAGNOSTIC_TEST

Ultrasound based imaging of diaphragm muscle activity

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- Adult male and female healthy volunteers. Exclusion Criteria: * Volunteers who are pregnant. * Volunteers with known pulmonary pathology (COPD, asthma requiring routine treatment).

Locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

RECRUITING

Outcomes

Primary Outcomes

Shear wave speed

Elastography of the diaphragm muscle across various behaviors and conditions

Time frame: 3 hours

Data from ClinicalTrials.gov

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