The study aims to describe the current use of dalbavancin among diabetic patients with infections in a real-world clinical setting in Italy and Spain.
The study aims to describe the current use of dalbavancin in diabetic patients suffering from infections proven or suspected to be caused by Gram-positive or mixed Gram-positive and Gram-negative bacteria (with dalbavancin chosen for treating the Gram-positive component) in Italy and Spain. As overall strategies to reduce the risk of developing severe infections and poor treatment outcomes among diabetic patients are under-researched and should be explored. This study could increase the knowledge of infection management among diabetic patients treated with dalbavancin in order to support appropriate clinical decision-making.
Study Type
OBSERVATIONAL
Enrollment
98
Adult diabetic patients suffering from infections who received the last dose of dalbavancin according to the current standard clinical practice at least 30 (+7) days before enrolment in the study.
Ospedale Cardinal Massaia
Asti, Italy
Azienda Ospedaliera Universitaria Federico II
Napoli, Italy
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone"
Palermo, Italy
Retrospective description of the dalbavancin treatment in diabetic patients.
Evidence of dalbavancin treatment choice (number and dates of infusions)
Time frame: 4 weeks
Retrospective description of the utilization of dalbavancin treatment in diabetic patients.
Evidence of dalbavancin treatment choice (starting and subsequent dosage)
Time frame: 4 weeks
Retrospective description of the setting of dalbavancin treatment in diabetic patients.
Evidence of dalbavancin treatment choice (setting of infusion)
Time frame: 4 weeks
Demographic data
Demographic data description (Age and Gender)
Time frame: 4 weeks
Clinical cure of dalbavancin
Number of patients with clinical cure evaluated by physicians at end of dalbavancin treatment (i.e., date of last dalbavancin dose administration). Clinical cure is defined as clinical signs and symptoms resolved.
Time frame: Up to 8 weeks
Microbiological success of dalbavancin
Number of patients with microbiological success at end of dalbavancin treatment (i.e., date of last dalbavancin dose administration). Microbioligical success is defined as culture-confirmed eradication of the Gram-positive pathogens identified at baseline, documented as a negative bacterial culture from the same site as the initial positive baseline culture
Time frame: Up to 8 weeks
Incidence of Adverse Events
Safety profile was assessed through the incidence of Adverse Events occurred in patients treated with dalbavancin.
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A.O.U. Pisana Presidio Ospedaliero Cisanello
Pisa, Italy
Azienda Sanitaria Universitaria Friuli Centrale
Udine, Italy
ASST dei Sette Laghi
Varese, Italy
Hospital Universitario Fundación Alcorcón
Alcorcón, Madrid, Spain
Hospital Clinic
Barcelona, Spain
Hospital Universitario Virgen de las Nieves
Granada, Spain
Hospital Universitario La Paz
Madrid, Spain
...and 1 more locations
Time frame: Up to 8 weeks