Ultrasonographic Evaluation of the Diaphragm During NHF Versus NIV Use in Respiratory Failure

Jens Bräunlich35 enrolled

Overview

This study will describe influence of NHF or NIV to different ultrasonographic parameters of the diaphragm. Therefor subjects will be randomized to the sequence NHF and than NIV or NIV and than NHF. In all subjects same parameters will be evaluated.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Diaphragm Issues Respiratory Failure With Hypoxia Respiratory Failure With Hypercapnia Non-invasive Mechanical Ventilation

Interventions

DTEEDIAGNOSTIC_TEST

endexpiratory diaphragm thickness in mm

DTEIDIAGNOSTIC_TEST

endinspiratory diaphragm thickness in mm

DExDIAGNOSTIC_TEST

diaphragm excursion during rest and diaphragmatic excursion during maximal inspiration in mm

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * acute or chronic respiratory failure, hyperemic or hypercapnic * age \> 18 yrs * written consent Exclusion Criteria: * critical disease (intubation, heart failure, lung edema,..) * no compliance * metabolic acidosis

Locations (1)

University of Leipzig

Leipzig, Germany

RECRUITING

Outcomes

Primary Outcomes

Changes in DTEE

Evaluation from baseline and between devices

Time frame: 10 minutes

Secondary Outcomes

Changes in DTEI

Evaluation from baseline and between devices

Time frame: 10 minutes

Changes in Dex

Evaluation from baseline and between devices

Time frame: 10 minutes

Data from ClinicalTrials.gov

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