Dual-Energy/Multi-Energy/Spectral-CT can visualize bone marrow edema associated with fractures, however, current scientific evidence is mostly derived from to retrospective analyses. Our prospective study systematically analyzes the diagnostic accuracy of the visualization of bone marrow edema by including patients who are scheduled for a CT scan to exclude or further characterize a fracture. After giving informed consent, the CT scan will be performed using a dose-neutral Dual-Energy-/Multi-Energy-/Spectral-CT acquisition technique. If the patient undergoes MRI of the same region within 7 days, this scan will be used as a gold-standard for bone marrow edema. This will allow the quantification of diagnostic accuracy.
Study Type
OBSERVATIONAL
Enrollment
800
CT acquisition using a Dual-Energy / Multi-Energy / Spectral acquisition mode
CT acquisition using a standard single energy / non-spectral acquisition mode
University Hospital Augsburg
Augsburg, Bavaria, Germany
RECRUITINGDiagnostic Accuracy of Dual-Energy/Multi-Energy/Spectral CT to detect bone marrow edema in comparison with MRI as the goldstandard.
sensitivity, specificity and positive and negative likelihood ratios will be assessed
Time frame: MRI of the same region can be used for comparison if performed within 7 days
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