Knee replacements are the second most common surgery in Canada. Most patients recover very well but research consistently shows that 1 in 5 patients still have pain many months after surgery. Doctors often prescribe opioid medications for pain after surgery (e.g. Percocet, hydromorphone, codeine). These medications can be helpful for some people, but they can also be dangerous, particularly when used for a long time. Many patients don't like the way opioids make them feel and would prefer alternative pain management strategies. Some people become addicted to opioids, have a difficult time reducing the dose of opioids, or have lasting health problems after using them. People in this study will be randomized to either have usual care or a new pathway designed to improve pain control and decrease opioid use after knee replacements. This study will have an intervention coordinator who will assess patients before surgery and who will follow up with patients regularly after surgery to make sure their pain is controlled and to avoid long-term opioid use. This study will use education, physiotherapy, psychological therapy, ice/cold, and non-opioid pain medications. As pain medications may work differently in different patients, the coordinator will check on each patient to look for pain control and assist to reduce the amount of opioids used after surgery. This study will help people have safer and more effective pain management after surgery which may lead to better recovery, higher satisfaction, and a lower risk of being harmed by opioids after surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
102
Pre-operative pain education and expectation setting, identification and modification of risk factors in high risk patients, postoperative individualized analgesic prescriptions, and continued support for pan control and recovery facilitated by an interventions coordinator.
Standard perioperative care, surgical treatment, and pain medications.
St. Joseph's Healthcare Hamilton
Hamilton, Ontario, Canada
Intervention adherence [feasibility]
Percentage of patients receiving at least 3 of the 4 trial intervention components.
Time frame: 8 weeks
Participant recruitment [feasibility]
Number of participants recruited
Time frame: 4 months
Participant retention [feasibility]
Number of participants completing the primary outcome
Time frame: 8 weeks
Opioid-free pain control
Three or more consecutive days of \<4/10 pain score on a 0-10 numeric rating scale (NRS; lower score is better) with no opioid use for the operated knee.
Time frame: 8 weeks
Chronic post-surgical pain (CPSP)
Defined by the International Classification of Diseases version-11 (ICD-11) criteria
Time frame: 12 months
CPSP intensity of resting and movement evoked pain
Measured on a 0-10 numeric rating scale (NRS; lower score is better)
Time frame: 12 months
Postoperative opioid use
Presence of daily opioid use, started after surgery or increased after surgery (binary)
Time frame: 12 months
Satisfaction with pain control
0 to 100 scale (0=extremely dissatisfied, 100=extremely satisfied)
Time frame: 12 months
Health related quality of life
EuroQol-5 Dimensions (EQ-5D)
Time frame: 12 months
Complications
Surgery-related and knee-related adverse events, pain medication related adverse events, and readmissions
Time frame: 12 months
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