Quantifying Gait Alteration in Multiple Sclerosis Using a Wearable Device

Nantes University Hospital44 enrolled

Overview

Gait alteration is frequent in MS and limitation in walking ability is a major concern in MS patients. The development of wearable device offers the opportunity to collect data during daily activity including walking.

Umanit and LMJ (Nantes university) has developed a device call eMSgait to assess walking ability in MS patients individuals (eg MS patients). This device consists in a commercialized IMU sensor (MetaMotionR Sensor, Mbientilab) worn at the right hip, a smartphone app and dedicated algorithm/mathematical model to extract raw sensor data and calculate individual gait pattern (IGP). This IGP consists of a curve, based on quaternion and representing the rotation recorded by the IMU during an average gait cycle. Pursue first pilot work assessing information from IGP on gait alteration in MS.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Multiple Sclerosis

Interventions

Wearable sensorOTHER

IMU sensor (as part of eMSGait device) worn at the hip during T25FW

Eligibility

Sex: ALLMin age: 18 YearsMax age: 64 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 - 64 years * Diagnosis of MS based on McDonald criteria (including Relapsing-remitting and progressive MS) * No relapse within the last 5 weeks before recruitment * Able to walk with or without assistance/help/aid (one or 2 canes) * EDSS \[0-6\] Exclusion Criteria: * Women who are pregnant * Patient having expressed their opposition * Patient under guardianship or security measure

Locations (1)

Nantes University Hospital

Nantes, Loire-Atlantique, France

Outcomes

Primary Outcomes

Correlation with disability

Correlation of gait measures (mean amplitude of walking cycles (m), mean duration of walking cycles (s), Stance swing phase ratio) obtained during a walk of 25 feet with Expanded Disability Status Scale (EDSS). EDSS is an ordinal scale measuring disability and ranging from 0 (normal examination) to 10 (death due to MS) in a 0,5-point increments from score 1.