To investigate the effect of co existance of diabetes mellitus and chronic kidney disease on basic coagulation profile in comparison with diabetic patients with normal kidney function and non diabetic patients with chronic kidney disease
We will study impact of type 2 diabetes mellitus on basic coagulation profile and platelet indices among patients with chronic kidney disease
Study Type
OBSERVATIONAL
Enrollment
150
Study basic coagulation profile and platelet indices among diabetic patients with chronic kidney disease
Sohag University
Sohag, Egypt
Estimate risk of thrombosis or bleeding for the 3 study groups by prothrombin time
We will include 150 patients and classify them into 3 groups each one consists of 50 patients First group those patients with diabetes mellitus only Second group those patients with chronic kidney disease only Third group those patients with combined diabetes mellitus type 2 and chronic kidney disease not on hemodialysis First we will measure prothrombin time
Time frame: 1 day
Estimate risk of thrombosis or bleeding for the 3 study groups by prothrombin concentration
We will include 150 patients classified into 3 groups as previous Second measure is prothrombin concentration
Time frame: 1 day
Estimate risk of thrombosis or bleeding for the 3 study groups by INR
We will include 150 patients as previous Third measure is INR ( international normalised ratio )
Time frame: 1 day
Estimate risk of thrombosis or bleeding for the 3 study groups by partial thromboplastin time
We will include 150 patients as previous Fourth measure is partial thromboplastin time
Time frame: 1 day
Estimate risk of thrombosis or bleeding for the 3 study groups by serum fibrinogen
We will include 150 patients as previous Fifth measure is serum fibrinogen level in the 3 groups
Time frame: 1 day
Estimate risk of thrombosis or bleeding for the 3 study groups by mean platelet volume
We will include 150 patients as previous Sixth measure is mean platelet volume in the 3 groups
Time frame: 1 day
Estimate risk of thrombosis or bleeding for the 3 study groups by platelet distribution width
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We will include 150 patients as previous Seventh measure is platelet distribution width for the 3 groups
Time frame: 1 day
Estimate risk of thrombosis or bleeding for the 3 study groups by plateletcrit
We will include 150 patients as previous Eighth measure is plateletcrit of the 3 study groups
Time frame: 1 day