Patogenic Mutation in 5 Genes

Dr Cipto Mangunkusumo General Hospital22 enrolled

Overview

This is a pathogenic mutation profile of colorectal patients specifically in 5 genes, i.e. APC, TP53, PIK3CA, KRAS, and MLH1. Single nucleotide variants identified were synchronized with patients' characteristics.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Colorectal Cancer APC Gene Mutation TP53 Gene Mutation PIK3CA Gene Mutation KRAS Mutation-Related Tumors MLH1 Gene Mutation

Interventions

co-occuring mutationOTHER

APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * FFPE samples fullfilling purity criterion and pass quality control Exclusion Criteria: * none

Locations (1)

Vania Myralda Giamour Marbun

Jakarta, ALL, Indonesia

Outcomes

Primary Outcomes

Description of clinical characteristics

Age, gender

Time frame: January 2017 - June 2021

Description of tumor nature

grade, stage, lymphovascular invasion, tumor location

Time frame: January 2017 - June 2021

Description of survival

Median of life expectancy

Time frame: January 2017 - June 2021

Data from ClinicalTrials.gov

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