The purpose of this study is to evaluate the effect of probiotic administration on TPN dependence in infants \< 32 weeks GA and BW 1500 grams or less in the Banner - University Medical Center Phoenix and Banner Children's at Desert Neonatal Intensive Care Units (NICU). The primary endpoint of capturing the number of days of TPN administration can reflect that an infant is progressing towards readiness for the initiation or advancement of enteral feedings at an earlier interval. The relationship between probiotic administration and the incidence of NEC, culture positive sepsis, and mortality is of interest to us and will be captured. Finally, the assessment of the tolerance of probiotic administration and the potential positive impact on growth and development in these premature infants may validate our current practices.
Study Type
OBSERVATIONAL
Enrollment
150
Probiotic dietary supplement, Similac Probiotic Tri-Blend
Banner Children's at Desert
Mesa, Arizona, United States
Banner University Medical Center Phoenix
Phoenix, Arizona, United States
Number of days on total parenteral nutrition
Evaluate the effects of a probiotic dietary supplement (Similac Probiotic Tri-Blend) on number of days on total parenteral nutrition (TPN) in infants admitted to the Neonatal Intensive Care Unit (NICU).
Time frame: 30 days
Impact on neonatal growth
Neonatal growth velocity may be impacted by the usage of probiotics in the Neonatal Intensive Care Unit.
Time frame: 30 days
Feeding Intolerance
The administration of probiotics may change the incidence of feeding intolerance
Time frame: 30 days
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